pentobarbital will lessen the level or effect of trazodone by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.pentobarbital will minimize the level or result of bexarotene by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.pentobarbital will lower the level or result of theophylline by influen